Opportunity Information: Apply for HT942525ALSRPTDA

The FY25 DOD Amyotrophic Lateral Sclerosis Research Program (ALSRP) Therapeutic Development Award funds research aimed at advancing ALS treatments from preclinical validation through studies that enable FDA Investigational New Drug (IND) applications. Projects must be product-driven, starting with candidate compounds that have already shown proof-of-concept efficacy in at least one ALS preclinical model, whether in animals or cell systems.

Researchers new to ALS are encouraged to collaborate with experts who have deep experience in ALS models, outcomes, and disease mechanisms. A key requirement is the parallel development or integration of mechanism-specific biomarkers that can enhance therapeutic trials by improving patient selection, refining trial design, and validating target engagement. Biomarkers developed solely for diagnosis, disease staging, or progression monitoring without direct ties to therapeutic development will not be funded. Proposals involving therapeutic candidates that already have an IND are not eligible.

  • The Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DOD Amyotrophic Lateral Sclerosis, Therapeutic Development Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
  • This funding opportunity was created on 2025-04-18.
  • Applicants must submit their applications by 2025-08-27. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2025.)
  • The number of recipients for this funding is limited to 4 candidate(s).
  • Eligible applicants include: Unrestricted.
Apply for HT942525ALSRPTDA

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Funding Opportunity
DOD Amyotrophic Lateral Sclerosis, Therapeutic Idea Award Apply for HT942525ALSRPTIA

Funding Number: HT942525ALSRPTIA
Agency: Dept. of the Army -- USAMRAA
Category: Science and Technology and other Research and Development
Funding Amount: Case Dependent
Alzheimer’s Research Program Transforming Care Award Apply for HT942525AZRPTRCA

Funding Number: HT942525AZRPTRCA
Agency: Dept. of the Army -- USAMRAA
Category: Science and Technology and other Research and Development
Funding Amount: Case Dependent
DOD Amyotrophic Lateral Sclerosis, Clinical Outcomes and Biomarkers Award Apply for HT942525ALSRPCOBA

Funding Number: HT942525ALSRPCOBA
Agency: Dept. of the Army -- USAMRAA
Category: Science and Technology and other Research and Development
Funding Amount: Case Dependent
DOD Amyotrophic Lateral Sclerosis, Pilot Clinical Trial Award Apply for HT942525ALSRPPCTA

Funding Number: HT942525ALSRPPCTA
Agency: Dept. of the Army -- USAMRAA
Category: Science and Technology and other Research and Development
Funding Amount: Case Dependent
Alzheimer’s Research Program Transforming Diagnosis Award Apply for HT942525AZRPTRDA

Funding Number: HT942525AZRPTRDA
Agency: Dept. of the Army -- USAMRAA
Category: Science and Technology and other Research and Development
Funding Amount: Case Dependent
DoD Breast Cancer Clinical Research Extension Award Apply for HT942525BCRPCREA

Funding Number: HT942525BCRPCREA
Agency: Dept. of the Army -- USAMRAA
Category: Science and Technology and other Research and Development
Funding Amount: Case Dependent
DoD Breast Cancer Breakthrough Award Levels 1 and 2 Apply for HT942525BCRPBTA12

Funding Number: HT942525BCRPBTA12
Agency: Dept. of the Army -- USAMRAA
Category: Science and Technology and other Research and Development
Funding Amount: Case Dependent
DoD Breast Cancer Breakthrough Award Level 3 Apply for HT942525BCRPBTA3

Funding Number: HT942525BCRPBTA3
Agency: Dept. of the Army -- USAMRAA
Category: Science and Technology and other Research and Development
Funding Amount: Case Dependent
DoD Breast Cancer Era of Hope Scholar Award Apply for HT942525BCRPEOHS

Funding Number: HT942525BCRPEOHS
Agency: Dept. of the Army -- USAMRAA
Category: Science and Technology and other Research and Development
Funding Amount: Case Dependent

 

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